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Tottenham Hotspur are sweating over Cristian Romero’s fitness ahead of their next league game against Fulham.

The centre-back was replaced at the start of the second half in Argentina’s 2-0 win over Peru on Tuesday.

TyC Sports say ‘alarms go off’ in the national team after the Tottenham star was forced off due to discomfort in his right ankle.

It’s believed the 25-year-old hurt his ankle in a clash with Peru’s Paolo Guerrero in the first half.

The outlet states the World Cup winner tried to ‘calm the ailment’ using an ice pack, likely during the break, but that wasn’t helpful.

When Romero came on the pitch in the second half, TyC Sports claim he couldn’t handle the pain and then asked to be substituted. Real Betis defender Germán Pezzella came on for the Tottenham player.

The extent of the damage isn’t clear and both Ange Postecoglou and Spurs will be hoping the South American’s latest setback won’t force him to miss any games.

There should be more updates on Romero’s injury in the next few hours and that should clarify whether he’ll available for selection to face Fulham.